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Short Biography Ian James Martins is an Editor/Reviewer for Open Acess Pub/MDPI journals/other international journals. He is Advisory Board Member for Photon Journal. He is a Fellow of the International Agency for Standards and Ratings (IASR). He conferred with the RICHARD KUHN RESEARCH AWARD-2015 ENDOCRINOLOGY AND METABOLISM. He is Chief Editor for International Journal of Diabetes Research (2014-2019), Research and Reviews: Neuroscience (2016-2019) and Journal of Diabetes and Clinical Studies (2017-2019). He is BIT Member (BIT Congress. Inc) with an H-index of 65 and Scientist for The Science Advisory Board (USA) and an Academic with Academia.edu with citations >4800. Researchgate Analysis: RG score (>96%) of international Scientists. He acquired 71 International Certificates. He is a reviewer for approx. 47 journals over the past five years. Now he is in the 98th percentile as assessed for Publons users by merit. He is Advisory Committee and Organizing Board Member for various international conferences (2018-2019).
IMPACT OF PREVIOUS RESEARCH TO THE FIELD OF MEDICINE AND LABORATORY TECHNOLOGY THAT MAY AVOID INADVERTENT ERRORS AND MAY TRANSLATE TO COMMERCIALISATION OF MEDICAL RESEARCH THAT DETERMINE CRITICAL HEATLH OUTCOMES. Development of a BLOOD TEST has been of critical interest to the QUALITY CONTROL of plasma/sera samples for metabolic disease with relevance to diabetes and neurodegenerative diseases. RELEVANT PUBLICATIONS: 1. Sirtuin 1, a Diagnostic Protein Marker and its Relevance to Chronic Disease and Therapeutic Drug Interventions”. EC Pharmacology and Toxicology 6.4 (2018): 209-215. CERTIFICATE OF PUBLICATION. 2. Evaluation of diagnostic tests in human health and disease. J Clin Path Lab Med. 2018;2(1):13-15. SIRTUIN 1 ANALYSIS ON BLOOD/PLASMA SAMPLES SHOULD BE CONDUCTED IN APPROPRIATE PRESERVATIVE, UNDER FREEZE/THAW CONDITIONS, STORAGE CONDITIONS. Bacterial LPS should be conducted (Sirtuin 1 repression) to avoid bacterial contamination with long term storage. ONLINE REFERENCES: 1. The Future of Genomic Medicine Involves the Maintenance of Sirtuin 1 in Global Populations. Int J Mol Biol. 2017. 2. The Future of Biomarkers Tests and Genomic Medicine in Global Organ Disease. Arch Infect Dis Ther. 2017. 3. Bacterial Lipopolysaccharides Change Membrane Fluidity with Relevance to Phospholipid and Amyloid Beta Dynamics in Alzheimer’s Disease. J Microb Biochem Technol. 2016. 4. The Role of Clinical Proteomics, Lipidomics, and Genomics in the Diagnosis of Alzheimer’s Disease. Proteomes, 2016. 5. LPS Regulates Apolipoprotein E and A? Interactions with Effects on Acute Phase Proteins and Amyloidosis. Advances in Aging Research 2015. Dr Martins research with relevance to diet, diabetes and neurodegenerative diseases builds upon his past > 150 publications that generates outputs that will have relevant and significant impact to the global community. The incidence of diabetes and non alcoholic fatty liver disease (NAFLD) has been predicted to increase to 21% by 2050. Novel and critical elements of scholarly peer review provides information that the heat shock gene Sirtuin 1 is repressed with relevance to diabetes, neurological diseases and Alzheimer's disease. Major unsolved challenges to advances in biology may now provide evidence to reverse Sirtuin 1 dysfunction that is connected to primarily to heat shock protein metabolism and secondly to toxic amyloid beta metabolism with mitochondrial apoptosis in liver and brain cells. In the developing world increased levels of bacterial lipopolysaccharides repress the anti-aging gene Sirtuin 1 with the development of diabetes, neurodegenerative diseases and Alzheimer’s disease. Unhealthy diets accelerate Type 3 diabetes with the induction of NAFLD in Global Populations